Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16172062 | 0.91 | CSF3R (0.36) | CYP1A2FGFR1FGFR2 | |
| SCHEMBL16169683 | 0.91 | PLA2G2A (0.43) | CYP1A2CYP19A1CYP2C9CYP2C19PLA2G2A | |
| SCHEMBL16169673 | 0.87 | NOS3 (0.42) | CYP1A2CYP19A1CYP2C9CYP2C19PLA2G2A | |
| SCHEMBL18020389 | 0.86 | PLA2G2A (0.47) | CYP1A2CYP2C9CYP2C19PLA2G2ACYP2D6 | |
| SCHEMBL15805868 | 0.85 | NOS3 (0.41) | CYP1A2KDM4EFGFR1FGFR2 | |
| SCHEMBL16419737 | 0.85 | SMN1; SMN2 (0.48) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL16169687 | 0.85 | SMN1; SMN2 (0.48) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL15274996 | 0.84 | RXRA (0.40) | CYP1A2CYP19A1CYP2C9CYP2C19PLA2G2A | |
| SCHEMBL16169676 | 0.84 | RXRA (0.40) | CYP1A2CYP19A1CYP2C9CYP2C19PLA2G2A | |
| SCHEMBL16419742 | 0.84 | LTA4H (0.49) | CYP1A2CYP19A1CYP2C9CYP2C19PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | CELLCEUTIX CORPORATION (US) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | ALG1, CD44, MUC1 | CYP1A2 4240/4885CYP19A1 4661/4885CYP2C9 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.