Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 3/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30408508 | 0.90 | CA2 (0.41) | ENPP2CA2CA1TTR | |
| SCHEMBL1792101 | 0.90 | CA2 (0.41) | ENPP2CA2CA1TTR | |
| SCHEMBL8208672 | 0.83 | HTT (0.43) | CA2PRKD1ICAM1SELEPRKD3 | |
| SCHEMBL31818 | 0.81 | GPR3 (0.54) | ENPP2CA2CA1MAOAMAOB | |
| SCHEMBL22205186 | 0.77 | CA1 (0.53) | ENPP2CA2CA1MAPTHPGD | |
| SCHEMBL24343663 | 0.76 | KDM4E (0.50) | CHEK1WEE1MAPTHPGD | |
| SCHEMBL22330006 | 0.75 | ENPP2 (0.44) | ENPP2TTRMAPTHPGD | |
| SCHEMBL14410474 | 0.75 | MGLL (0.55) | ENPP2CA2CA1 | |
| SCHEMBL29219008 | 0.75 | ENPP2 (0.53) | ENPP2CA2CA1DYRK1A | |
| SCHEMBL25695834 | 0.74 | GPR3 (0.45) | ENPP2CA2CA1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | CELLCEUTIX CORPORATION (US) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308317-A1 | Polymeric Compounds And Methods Of Making And Using The Same | ALG1, CD44, MUC1 | ENPP2 340/4885CA2 2165/4885CA1 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.