Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174813 | 0.76 | GRIN2D (0.47) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL16175071 | 0.74 | ALDH1A1 (0.47) | TSHRTDP1ALDH1A1HPGDHIF1A | |
| SCHEMBL9899292 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDCYP3A4LMNAPDK1 | |
| SCHEMBL669971 | 0.73 | TSHR (0.44) | TSHRTDP1ALDH1A1HPGDHIF1A | |
| SCHEMBL10615908 | 0.72 | TSHR (0.44) | TSHRTDP1ALDH1A1HPGDHIF1A | |
| SCHEMBL16175307 | 0.70 | TSHR (0.41) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL374327 | 0.69 | EPAS1 (0.52) | TSHRTDP1ALDH1A1HPGDHIF1A | |
| SCHEMBL29763615 | 0.69 | EPAS1 (0.52) | TSHRTDP1ALDH1A1HPGDHIF1A | |
| SCHEMBL10980919 | 0.69 | TSHR (0.62) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL16174940 | 0.68 | ARNT (0.39) | TDP1ALDH1A1CYP3A4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2792667-B1 | DIPHENYLAMINE COMPOUND AND METHOD FOR PRODUCING SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-9550724-B2 | Diphenylamine compounds and production method thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20140336415-A1 | DIPHENYLAMINE COMPOUNDS AND PRODUCTION METHOD THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-11-13 | — | — | US | disclosed |
| EP-2792667-A1 | DIPHENYLAMINE COMPOUND AND METHOD FOR PRODUCING SAME | Ihara Chemical Industry Co., Ltd. (JP) | 2014-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336415-A1 | DIPHENYLAMINE COMPOUNDS AND PRODUCTION METHOD THEREOF | DDT, PAH, DDC | TSHR 1952/4885TDP1 1985/4885ALDH1A1 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.