Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174785 | 0.90 | CTRC (0.41) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16174813 | 0.89 | GRIN2D (0.47) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27679282 | 0.85 | VCAM1 (0.37) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL669971 | 0.79 | TSHR (0.44) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16175251 | 0.77 | MAPT (0.44) | TSHRALDH1A1LMNANPC1MAPT | |
| SCHEMBL10980919 | 0.75 | TSHR (0.62) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10061111 | 0.73 | TAAR1 (0.39) | TDP1MAPT | |
| SCHEMBL16174936 | 0.72 | MAPT (0.49) | TSHRTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL16175317 | 0.72 | MAPT (0.46) | ALDH1A1LMNANPC1MAPTRAB9A | |
| SCHEMBL7514813 | 0.72 | ALDH1A1 (0.56) | TSHRGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2792667-B1 | DIPHENYLAMINE COMPOUND AND METHOD FOR PRODUCING SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-9550724-B2 | Diphenylamine compounds and production method thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20140336415-A1 | DIPHENYLAMINE COMPOUNDS AND PRODUCTION METHOD THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-11-13 | — | — | US | disclosed |
| EP-2792667-A1 | DIPHENYLAMINE COMPOUND AND METHOD FOR PRODUCING SAME | Ihara Chemical Industry Co., Ltd. (JP) | 2014-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336415-A1 | DIPHENYLAMINE COMPOUNDS AND PRODUCTION METHOD THEREOF | DDT, PAH, DDC | TSHR 1952/4885GRIN2D 2363/4885GRIN3B 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.