SCHEMBL669971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16174813	0.85	GRIN2D (0.47)	TSHRTDP1ALDH1A1HSD17B10GRIN2D
	SCHEMBL4146537	0.81	PNMT (0.53)	TSHRPNMTTDP1ALDH1A1LOXL2
	SCHEMBL16175307	0.79	TSHR (0.41)	TSHRTDP1ALDH1A1HSD17B10GRIN2D
	SCHEMBL10980919	0.78	TSHR (0.62)	TSHRTDP1ALDH1A1HSD17B10GRIN2D
	SCHEMBL16174785	0.76	CTRC (0.41)	TSHRTDP1ALDH1A1GRIN2DGRIN3B
	SCHEMBL7514813	0.75	ALDH1A1 (0.56)	TSHRTDP1ALDH1A1HSD17B10GRIN2D
	SCHEMBL29702010	0.75	ALDH1A1 (0.56)	TSHRTDP1ALDH1A1HSD17B10GRIN2D
	SCHEMBL16174751	0.73	TSHR (0.36)	TSHRTDP1ALDH1A1HSD17B10CYP1A2
	SCHEMBL2145586	0.72	TDP1 (0.69)	TSHRTDP1ALDH1A1HSD17B10VCAM1
	SCHEMBL29918148	0.72	TDP1 (0.69)	TSHRTDP1ALDH1A1HSD17B10VCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.