Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046228 | 0.81 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL15322314 | 0.78 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL1688323 | 0.77 | CCKBR (0.42) | — | |
| SCHEMBL16589541 | 0.76 | CHRNB2 (0.37) | ESR2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL15321898 | 0.74 | — | — | |
| SCHEMBL6612657 | 0.74 | ADRB1 (0.42) | — | |
| SCHEMBL11992334 | 0.73 | ESR2 (0.36) | ESR2CHRNB2CHRNA4 | |
| SCHEMBL16175447 | 0.72 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL6825397 | 0.72 | — | — | |
| SCHEMBL20308980 | 0.71 | PNMT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309551-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014273-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-21 | — | — | WO | disclosed |