SCHEMBL1618166

SCHEMBL1618166

O=C(Cl)c1ccc2c(c1)C(=O)N(c1ccccc1)C2=O

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.61
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
GFER P55789 1/20 0.59
ALDH1A1 P00352 3/20 0.59
CA9 Q16790 6/20 0.58
CA12 O43570 5/20 0.58
CA1 P00915 5/20 0.58
CA2 P00918 4/20 0.58
SCN2A Q99250 1/20 0.58
CA7 P43166 2/20 0.58
CA4 P22748 3/20 0.54
POLB P06746 2/20 0.53
MAPT P10636 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
HSD17B10 Q99714 1/20 0.52
APEX1 P27695 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1994560 0.90 CA9 (0.57) ESR1KMT2AMEN1GFERALDH1A1
SCHEMBL1995596 0.89 S100B (0.57) ESR1KMT2AMEN1ALDH1A1POLB
SCHEMBL17281691 0.87 PTGES (0.61) KMT2AMEN1GFERALDH1A1CA9
SCHEMBL9482780 0.87 APEX1 (0.66) ESR1KMT2AMEN1GFERALDH1A1
SCHEMBL1618163 0.87 KMT2A (0.76) ESR1KMT2AMEN1GFERALDH1A1
SCHEMBL15081236 0.81 CA9 (0.51) ESR1KMT2AMEN1GFERALDH1A1
SCHEMBL1618305 0.80 ALDH1A1 (0.70) ESR1KMT2AMEN1GFERALDH1A1
SCHEMBL10098939 0.80 ALDH1A1 (0.59) ESR1KMT2AMEN1GFERALDH1A1
SCHEMBL10098943 0.80 CA12 (0.64) ESR1KMT2AMEN1GFERALDH1A1
SCHEMBL9339007 0.80 CA9 (0.77) KMT2AMEN1GFERALDH1A1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923184-B2 Photoconductors containing trimellitimide esters EASTMAN KODAK COMPANY (US) 2011-04-12 US disclosed
US-7923184-B2 Photoconductors containing trimellitimide esters EASTMAN KODAK COMPANY (US) 2011-04-12 US disclosed
US-20090087762-A1 PHOTOCONDUCTORS CONTAINING TRIMELLITIMIDE ESTERS BANK OF AMERICA, N.A., AS AGENT 2009-04-02 US disclosed
US-3941749-A FILMS, FILAMENTS WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-03-02 US disclosed