Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618166 | 0.89 | ESR1 (0.61) | MEN1KMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL4230581 | 0.86 | S100B (0.74) | S100BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1994560 | 0.85 | CA9 (0.57) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL9458520 | 0.82 | TDP1 (0.77) | S100BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9564308 | 0.81 | HSD17B10 (0.72) | S100BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17946076 | 0.80 | TDP1 (0.57) | S100BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5012357 | 0.79 | HSD17B10 (0.66) | S100BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9803540 | 0.79 | TDP1 (0.72) | S100BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28802045 | 0.78 | PARP1 (0.56) | S100BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17281691 | 0.77 | PTGES (0.61) | MEN1KMT2AALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338485-A1 | Substituted 1,3-dioxoisoindolines as medicine | Grünenthal GmbH (DE) | 2011-06-29 | — | — | EP | disclosed |