SCHEMBL16182631

SCHEMBL16182631

CC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(NC(=O)CCCCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.67
▸ NOD1 Q9Y239 4/20 0.46
▸ CCKAR P32238 3/20 0.43
▸ CCKBR P32239 3/20 0.43
▸ FOLH1 Q04609 3/20 0.41
▸ GLO1 Q04760 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18697474 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL13293965 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL12806533 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24284196 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL12287742 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24198476 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL23051891 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24899310 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL20911267 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL19243816 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649269-B2 Bifunctional compounds comprising insulin peptides and EGF(A) peptides NOVO NORDISK A/S (DK) 2023-05-16 — — US disclosed
WO-2022268029-A1 TRIPLE AGONIST FOR GLP-1, GCG AND GIP RECEPTORS 广东东阳光药业有限公司 2022-12-29 — — WO disclosed
US-20220204580-A1 POLYPEPTIDES AND USES THEREOF MEDIMMUNE LIMITED (GB) 2022-06-30 — — US disclosed
US-20220009989-A1 BIFUNCTIONAL COMPOUNDS COMPRISING INSULIN PEPTIDES AND EGF(A) PEPTIDES NOVO NORDISK A/S (DK) 2022-01-13 — — US disclosed
US-20140315797-A1 Novel N-Terminally Modified Insulin Derivatives NOVO NORDISK A/S (DK) 2014-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649269-B2 Bifunctional compounds comprising insulin peptides and EGF(A) peptides IAPP, IGFBP1, IGFBP2 GLP1R 16/4885NOD1 2091/4885CCKAR 430/4885
US-20220204580-A1 POLYPEPTIDES AND USES THEREOF IAPP, IGFBP2, IGFBP4 GLP1R 13/4885NOD1 3647/4885CCKAR 2400/4885
US-20140315797-A1 Novel N-Terminally Modified Insulin Derivatives IAPP, INSR, IRS1 GLP1R 12/4885NOD1 428/4885CCKAR 186/4885
US-20220009989-A1 BIFUNCTIONAL COMPOUNDS COMPRISING INSULIN PEPTIDES AND EGF(A) PEPTIDES IAPP, IGFBP1, IGFBP2 GLP1R 16/4885NOD1 2091/4885CCKAR 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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