Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.35 |
| ▸ | HTR2A | P28223 | 7/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.31 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16190013 | 0.76 | EED (0.34) | HTR2CHTR2AHTR2BMAPTKIF11 | |
| SCHEMBL31634038 | 0.76 | EED (0.34) | HTR2CHTR2AHTR2BMAPTKIF11 | |
| SCHEMBL10188136 | 0.73 | MAPT (0.37) | MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL14203441 | 0.72 | HTR2C (0.36) | HTR2CHTR2AHTR2B | |
| SCHEMBL945134 | 0.71 | ITGB2 (0.42) | SLC9A1SLC9A5SLC9A2KIF11 | |
| SCHEMBL31394265 | 0.70 | LPL (0.35) | — | |
| Bromide SCHEMBL2483355 | 0.69 | ITGB2 (0.41) | SLC9A1SLC9A5SLC9A2KIF11 | |
| SCHEMBL25723254 | 0.69 | PKM (0.32) | HTR2CHTR2AMAPT | |
| SCHEMBL10818074 | 0.69 | MAPT (0.44) | HTR2CHTR2AHTR2BMAPTGAA | |
| SCHEMBL13547884 | 0.68 | HTR2C (0.36) | HTR2CHTR2AHTR2BKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014169845-A2 | 4,5-DIHYDRO-PYRAZOLO [3, 4-C] PYRID-2-ONES, PREPARATION METHOD AND APPLICATION THEREOF | 四川海思科制药有限公司 (CN) | 2014-10-23 | — | — | WO | disclosed |