Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | GCGR | P47871 | 9/20 | 0.43 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1690308 | 0.79 | PTGDR2 (0.62) | PTGDR2 | |
| SCHEMBL27658661 | 0.76 | GPBAR1 (0.41) | GPBAR1 | |
| SCHEMBL16199785 | 0.72 | PTGDR2 (0.70) | PTGDR2FFAR1 | |
| SCHEMBL29633908 | 0.70 | DAO (0.49) | PTGDR2RXRANR1H2FFAR4FFAR1 | |
| SCHEMBL12835379 | 0.70 | DAO (0.49) | PTGDR2RXRANR1H2FFAR4FFAR1 | |
| SCHEMBL3928210 | 0.69 | AGBL2 (0.68) | PTGDR2RXRANR1H2FFAR4FFAR1 | |
| SCHEMBL26679370 | 0.69 | RXRA (0.50) | PTGDR2RXRANR1H2FFAR1CYSLTR2 | |
| SCHEMBL29009780 | 0.69 | MGLL (0.47) | PTGDR2RXRANR1H2FFAR4FFAR1 | |
| SCHEMBL11524595 | 0.68 | MGLL (0.47) | PTGDR2RXRANR1H2FFAR4FFAR1 | |
| SCHEMBL4007916 | 0.67 | FFAR1 (0.58) | PTGDR2GCGRRXRAFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611091-B1 | Substituted phenylalkanoic acid derivatives and their use for respiratory disease treatment | ASTRAZENECA AB (SE) | 2014-10-29 | — | — | EP | disclosed |