Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184160 | 0.87 | PDE2A (0.32) | PTGS2 | |
| SCHEMBL13066182 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL16200214 | 0.77 | ADORA2A (0.40) | PTGS2PTGS1 | |
| SCHEMBL13066184 | 0.75 | PTGS2 (0.33) | PTGS2PTGS1 | |
| SCHEMBL19228477 | 0.74 | CCR1 (0.37) | — | |
| SCHEMBL5275680 | 0.71 | SLC9A1 (0.31) | — | |
| SCHEMBL15069893 | 0.68 | ADORA2A (0.31) | — | |
| SCHEMBL16200051 | 0.65 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL16200397 | 0.63 | KDM4E (0.33) | — | |
| SCHEMBL14044106 | 0.63 | PTGS2 (0.43) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |