Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.61 |
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | CFD | P00746 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | F2R | P25116 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13476524 | 0.86 | MGLL (0.68) | MGLLHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL7404383 | 0.84 | MGLL (0.66) | MGLLHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL4003283 | 0.84 | MITF (0.72) | MGLLHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL8404715 | 0.84 | L3MBTL1 (0.67) | MGLLHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL7568726 | 0.83 | ALDH1A1 (0.70) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6098738 | 0.83 | CFD (0.81) | MGLLHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL725251 | 0.82 | EPHX2 (0.63) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL12366199 | 0.81 | MGLL (0.62) | MGLLHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL12383061 | 0.81 | F2R (0.77) | MGLLHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL6037929 | 0.81 | HDAC6 (0.79) | MGLLHDAC6HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014175832-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-30 | — | — | WO | disclosed |