SCHEMBL16202057

SCHEMBL16202057

CCO/N=C(\C)c1ccc(C)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.51
PPARA Q07869 3/20 0.51
ALDH1A1 P00352 2/20 0.47
MAPT P10636 4/20 0.47
NPY1R P25929 1/20 0.47
NPY2R P49146 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.43
LMNA P02545 2/20 0.43
PTBP1 P26599 1/20 0.43
HTT P42858 2/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
RXRA P19793 2/20 0.37
RXRG P48443 2/20 0.37
GABRA1 P14867 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17217588 0.86 NPC1 (0.48) PPARGPPARAALDH1A1MAPTSMN1; SMN2
SCHEMBL16202082 0.86 LMNA (0.41) PPARGPPARAALDH1A1SMN1; SMN2LMNA
SCHEMBL15851161 0.86 NPC1 (0.48) PPARGPPARAALDH1A1MAPTSMN1; SMN2
SCHEMBL16202013 0.83 SMN1; SMN2 (0.48) PPARGPPARAALDH1A1MAPTNPY1R
SCHEMBL7941466 0.82 PPARG (0.38) PPARGPPARAALDH1A1MAPTNPY1R
SCHEMBL7941464 0.82 PPARG (0.38) PPARGPPARAALDH1A1MAPTNPY1R
SCHEMBL16202071 0.81 PPARG (0.41) PPARGPPARAALDH1A1MAPTSMN1; SMN2
SCHEMBL16202063 0.80 PPARG (0.47) PPARGPPARAALDH1A1MAPTNPY1R
SCHEMBL16202056 0.79 MAPT (0.50) PPARGPPARAALDH1A1MAPTNPY1R
SCHEMBL13683674 0.79 SMN1; SMN2 (0.52) PPARGPPARAALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2016-09-01 US disclosed
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-26 US disclosed
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi BASF SE (DE) 2016-05-26 US disclosed
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-05 US disclosed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US disclosed
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI SNX1, DPM1, SNU13 PPARG 4783/4885PPARA 4737/4885ALDH1A1 2106/4885
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI DPM1, CROCC, SNX1 PPARG 4807/4885PPARA 4680/4885ALDH1A1 3309/4885
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi DPM1, CROCC, SNX1 PPARG 4807/4885PPARA 4680/4885ALDH1A1 3309/4885
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB PPARG 4391/4885PPARA 4457/4885ALDH1A1 2278/4885
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB PPARG 4391/4885PPARA 4457/4885ALDH1A1 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.