SCHEMBL16202079

SCHEMBL16202079

CCC/C(=N\OCC)c1cc(C)c(C)cc1C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.34
RXRG P48443 2/20 0.34
RXRB P28702 1/20 0.34
DRD4 P21917 5/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
SLC6A4 P31645 2/20 0.32
SMN1; SMN2 Q16637 3/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16202067 0.84 GSK3B (0.39) DRD4SLC6A4SMN1; SMN2KMT2AKDM4E
SCHEMBL16202030 0.77 RXRA (0.36) RXRARXRGRXRBPPARGPPARA
SCHEMBL16202071 0.69 PPARG (0.41) RXRARXRGRXRBDRD4PPARG
SCHEMBL12997575 0.68 ALDH1A1 (0.33) PPARGPPARASMN1; SMN2KMT2AKDM4E
SCHEMBL4876192 0.66 NR1H2 (0.45) DRD4PPARGPPARASLC6A4SMN1; SMN2
SCHEMBL4876198 0.66 NR1H2 (0.45) DRD4PPARGPPARASLC6A4SMN1; SMN2
SCHEMBL23544604 0.66 HPGD (0.53) SMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL17233213 0.66 MAPT (0.49) RXRARXRGRXRBDRD4PPARG
SCHEMBL13606907 0.64 PPARG (0.36) RXRARXRGRXRBDRD4PPARG
SCHEMBL16202068 0.64 DRD4 (0.49) DRD4PPARGPPARASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2016-09-01 US disclosed
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-26 US disclosed
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi BASF SE (DE) 2016-05-26 US disclosed
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-05 US disclosed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US disclosed
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI SNX1, DPM1, SNU13 RXRA 4465/4885RXRG 4376/4885RXRB 4450/4885
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI DPM1, CROCC, SNX1 RXRA 4379/4885RXRG 4122/4885RXRB 4400/4885
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi DPM1, CROCC, SNX1 RXRA 4379/4885RXRG 4122/4885RXRB 4400/4885
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB RXRA 4724/4885RXRG 4552/4885RXRB 4037/4885
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB RXRA 4724/4885RXRG 4552/4885RXRB 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.