Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16203407 | 0.82 | IKBKB (0.42) | ALDH1A1HSD17B10P2RX3P2RX2CA12 | |
| SCHEMBL31243809 | 0.81 | AKR1C3 (0.48) | AKR1C3AKR1C2AKR1C1ALDH1A1HSD17B10 | |
| SCHEMBL24061499 | 0.81 | NUDT1 (0.43) | ALDH1A1HSD17B10MAPK1P2RX3P2RX2 | |
| SCHEMBL20754892 | 0.79 | METAP2 (0.37) | AKR1C3AKR1C2AKR1C1ALDH1A1HSD17B10 | |
| SCHEMBL30597431 | 0.77 | ALDH1A1 (0.52) | AKR1C3AKR1C2AKR1C1ALDH1A1HSD17B10 | |
| SCHEMBL27333267 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MAPK1P2RX3P2RX2 | |
| SCHEMBL636376 | 0.77 | GABRA1 (0.58) | GABRA1GABRB1CA1CA2POLB | |
| SCHEMBL15975997 | 0.77 | ESR2 (0.44) | AKR1C3AKR1C2AKR1C1ALDH1A1HSD17B10 | |
| Bromide SCHEMBL9491638 | 0.75 | GABRA1 (0.56) | GABRA1GABRB1CA1CA2POLB | |
| SCHEMBL16203402 | 0.74 | CA1 (0.46) | GABRA1GABRB1ALDH1A1HSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160079547-A1 | BLUE LUMINESCENT COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2016-03-17 | — | — | US | disclosed |
| WO-2014176159-A9 | BLUE LUMINESCENT COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-02-19 | — | — | WO | disclosed |
| WO-2014176159-A1 | BLUE LUMINESCENT COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160079547-A1 | BLUE LUMINESCENT COMPOUNDS | HBS1L, IK, LAS1L | GABRA1 4208/4885GABRB1 4218/4885AKR1C3 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.