SCHEMBL636376

SCHEMBL636376

CC(C)c1cc(Br)cc(C(C)C)c1N

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.58
GABRB1 P18505 3/20 0.58
GAA P10253 2/20 0.36
POLB P06746 1/20 0.36
GFER P55789 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL9491638 0.97 GABRA1 (0.56) GABRA1GABRB1GAAPOLBGFER
SCHEMBL17262069 0.88 GABRA1 (0.52) GABRA1GABRB1GAAPOLBGFER
SCHEMBL3601427 0.86 GABRA1 (0.50) GABRA1GABRB1GAAPOLBGFER
SCHEMBL31506856 0.86 GABRA1 (0.50) GABRA1GABRB1GAAPOLBGFER
SCHEMBL20180215 0.85 GABRA1 (0.45) GABRA1GABRB1GAAPOLBGFER
SCHEMBL21077346 0.84 GABRA1 (0.48) GABRA1GABRB1GAAPOLBGFER
SCHEMBL20681258 0.83 GABRA1 (0.64) GABRA1GABRB1GAAPOLBGFER
SCHEMBL461449 0.78 CA1 (0.55) GABRA1GABRB1GAAPOLBGFER
SCHEMBL2155116 0.78 ALDH1A1 (0.38) GABRA1GABRB1GAAPOLBGFER
SCHEMBL16203403 0.77 GABRA1 (0.41) GABRA1GABRB1GAAPOLBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118988254-B Adsorbent for removing perchlorate in water and preparation method and application thereof 湖南大学 2025-01-03 CN claimed
CN-118988254-A Adsorbent for removing perchlorate in water and preparation method and application thereof 湖南大学 2024-11-22 CN claimed
CN-116693816-A Palladium-nitrogen heterocyclic carbene skeleton organic porous polymer, and preparation method and application thereof 泰山学院 2023-09-05 CN claimed
CN-112250547-B Phenol recovery method for potassium phenol-containing wastewater from production of diafenthiuron 襄阳金达成精细化工有限公司 2022-11-22 CN claimed
CN-115322154-A Synthesis method of 1, 3-bis (4-carboxyphenyl-2, 6-diisopropyl) imidazolium chloride 上海师范大学 2022-11-11 CN claimed
CN-114957066-A Energy-saving and efficient synthesis method of diafenthiuron 江苏长青农化南通有限公司 2022-08-30 CN claimed
CN-113651705-A 4-phenoxy-2, 6-diisopropylaniline intermediate and preparation method and application thereof 襄阳金达成精细化工有限公司 2021-11-16 CN claimed
CN-106109224-B A kind of middle burnt logical tune therapeutic equipment and its preparation method of use and critical component 史文凌 2018-03-13 CN claimed
CN-106109224-A A kind of middle Jiao leads to tune therapeutic instrument and use thereof and the manufacture method of critical component 史文凌 2016-11-16 CN claimed
WO-1999048847-A1 AROMATIC BROMINATION PROCESS ALBEMARLE CORPORATION (US) 1999-09-30 WO claimed
US-5907063-A REACTION WITH HYDROGEN BROMIDE IN THE PRESENCE OF SULFOXIDE ALBEMARLE CORPORATION (US) 1999-05-25 US claimed
CN-122010847-A Synthesis method of 1- [3, 5-bis (1-methylethyl) [1,1' -biphenyl ] -4-yl ] -2-bromo-1H-benzimidazole 安徽大学 2026-05-12 CN disclosed
CN-121824537-A Perylene diimide compound and synthetic method and application thereof 北京大学 2026-04-10 CN disclosed
US-20260042791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-12 US disclosed
US-20250318422-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-10-09 US disclosed
US-4897424-A Aryloxyphenylthioureas, aryloxyphenylisothioureas and aryloxyphenylcarbodiimides and pesticidal compositions containing them CIBA-GEIGY CORPORATION (US) 1990-01-30 US disclosed
EP-0296120-A2 Aryloxyphenyl ureas, isothio ureas and carbodiimides, their preparation and their use for the control of pests CIBA-GEIGY AG (CH) 1988-12-21 EP disclosed
US-4404402-A PLANT GROWTH REGULATING NITROANILINES AMERICAN CYANAMID COMPANY (US) 1983-09-13 US disclosed
WO-1982003390-A1 ERIVATIVES OF PHENOXY-PHENYLE-ISOTHIO-UREA,INTERMEDIARY PRODUCTS BASED ON PHENOXY-PHENYLE-THIO-UREA,PREPARATION THEREOF AND THEIR UTILIZATION AGAINST INSECTS CIBA GEIGY AG (CH) 1982-10-14 WO disclosed
US-4328247-A Phenoxyphenylisothioureas, production thereof and use thereof in pest control, and phenoxyphenylthioureas as intermediates for the production of the phenoxyphenylisothioureas and use thereof in pest control CIBA-GEIGY CORPORATION (US) 1982-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250318422-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRM1, OPRD1, LEF1 GABRA1 3078/4885GABRB1 2765/4885GAA 3424/4885
US-20260042791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRA1, MSL1 GABRA1 820/4885GABRB1 761/4885GAA 4150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.