Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216341 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTHCAR3ESPL1 | |
| SCHEMBL13465753 | 0.85 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL16216362 | 0.83 | AKR1C3 (0.41) | ALDH1A1SMN1; SMN2MAPTESPL1KMT2A | |
| SCHEMBL16207553 | 0.83 | AKR1C3 (0.41) | ALDH1A1SMN1; SMN2MAPTESPL1KMT2A | |
| SCHEMBL10777346 | 0.79 | GAA (0.45) | ALDH1A1SMN1; SMN2MAPTKMT2ATDP1 | |
| SCHEMBL25393016 | 0.78 | GAA (0.47) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL4856872 | 0.78 | ATM (0.46) | ALDH1A1SMN1; SMN2ATMTDP1 | |
| SCHEMBL14797548 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL30192959 | 0.78 | ATM (0.46) | ALDH1A1SMN1; SMN2ATMTDP1 | |
| SCHEMBL16216371 | 0.78 | MT-CO2 (0.40) | KMT2ALMNAMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799424-B1 | 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE | LTT BIO PHARMA CO LTD (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
| EP-2799424-A1 | 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE | LTT Bio-Pharma Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | FPR1, OPRK1, FPR2 | ALDH1A1 57/4885SMN1; SMN2 2380/4885MAPT 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.