Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212143 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL16212134 | 0.79 | GAA (0.44) | HTR2AHTR2CHTR2BTP53HTT | |
| SCHEMBL16212132 | 0.79 | GAA (0.44) | HTR2AHTR2CHTR2BTP53HTT | |
| SCHEMBL8102775 | 0.77 | HPGD (0.40) | KDM4EALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL25377395 | 0.75 | GAA (0.45) | KDM4EALDH1A1HTR2CHTR2BTP53 | |
| SCHEMBL31227382 | 0.75 | GAA (0.45) | KDM4EALDH1A1HTR2CHTR2BTP53 | |
| SCHEMBL16212174 | 0.75 | GAA (0.45) | KDM4EALDH1A1HTR2CHTR2BTP53 | |
| SCHEMBL16212172 | 0.75 | GAA (0.45) | KDM4EALDH1A1HTR2CHTR2BTP53 | |
| SCHEMBL16392349 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1TP53HTTMEN1 | |
| SCHEMBL27632012 | 0.72 | HTR2A (0.50) | HTR2AHTR2CHTR2BHRH3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2016-03-17 | — | — | US | disclosed |
| EP-2991487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177487-A9 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |
| WO-2014177487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | DNPH1, AADAC, NAAA | KDM4E 2020/4885ALDH1A1 3851/4885HTR2A 1908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.