SCHEMBL16215950

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13826009	0.92	ALDH1A1 (0.44)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2
	SCHEMBL20100709	0.90	ALDH1A1 (0.39)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2
	SCHEMBL24254708	0.87	CYP2C19 (0.41)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2
	SCHEMBL24254807	0.85	ALDH1A1 (0.38)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2
	SCHEMBL24254706	0.81	ALDH1A1 (0.38)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2
	SCHEMBL15909749	0.80	CYP1A2 (0.37)	ALDH1A1TDP1KDM4ECYP1A2CYP3A4
	SCHEMBL13826136	0.78	MAPT (0.38)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2
	SCHEMBL24254702	0.77	SYK (0.32)	ALDH1A1CYP3A4
	SCHEMBL27871421	0.77	ALDH1A1 (0.41)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2
	SCHEMBL24254694	0.77	ALDH1A1 (0.35)	ALDH1A1TDP1L3MBTL1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.