Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27245264 | 0.96 | MAPT (0.38) | MAPTTSHRLMNASMN1; SMN2CTSK | |
| SCHEMBL22124615 | 0.89 | ADORA1 (0.40) | KDM4ENPSR1ADORA1ADORA2AMEN1 | |
| SCHEMBL13826028 | 0.85 | MAPT (0.43) | MAPTTSHRLMNASMN1; SMN2CTSK | |
| SCHEMBL13826009 | 0.85 | ALDH1A1 (0.44) | MAPTTSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL29176116 | 0.81 | MAPT (0.41) | MAPTTSHRLMNASMN1; SMN2CTSK | |
| SCHEMBL16215950 | 0.78 | ALDH1A1 (0.42) | MAPTTSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL16122511 | 0.77 | ADORA1 (0.36) | MAPTTSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31145578 | 0.76 | MAPT (0.38) | MAPTTSHRLMNASMN1; SMN2CTSK | |
| SCHEMBL20657775 | 0.76 | ALDH1A1 (0.48) | MAPTTSHRLMNASMN1; SMN2CTSK | |
| SCHEMBL2453584 | 0.76 | MAPT (0.34) | MAPTTSHRLMNASMN1; SMN2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011026-A | Asymmetric bidentate phosphine ligand and synthesis method thereof | 淮北师范大学 | 2026-05-12 | — | — | CN | claimed |
| CN-122010810-A | The method comprises the following steps of18F-marked difluoromethyl seleno ether compound, and synthetic method and application thereof | 江苏省原子医学研究所 | 2026-05-12 | — | — | CN | claimed |
| CN-118994157-A | 3-Spiro indoline derivative containing trifluoromethyl and preparation method thereof | 西北师范大学 | 2024-11-22 | — | — | CN | claimed |
| CN-118812428-A | 3-Trifluoromethyl tetrahydroquinoline compound and preparation method thereof | 西北师范大学 | 2024-10-22 | — | — | CN | claimed |
| CN-117924125-A | Method for preparing sulfonamide derivative through visible light catalysis without metal participation | 苏州大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117800891-A | Preparation method of 3- (2-aminophenyl) pyrrole derivative | 深圳职业技术学院 | 2024-04-02 | — | — | CN | claimed |
| CN-117430542-B | Synthesis method of trifluoromethyl indole derivative | 上海恩氟佳科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117430542-A | Synthesis method of trifluoromethyl indole derivative | 上海恩氟佳科技有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117384178-A | Preparation method of 2, 3-dihydrobenzopyran-4-ketorolane derivatives | 深圳职业技术大学 | 2024-01-12 | — | — | CN | claimed |
| CN-117164533-A | Method for synthesizing furylacetic acid compound by using carbon dioxide | 中国科学院兰州化学物理研究所 | 2023-12-05 | — | — | CN | claimed |
| CN-117142943-A | Method for synthesizing 6-hydroxycaproic acid (ester) by using carbon dioxide and furfuryl alcohol compounds | 中国科学院兰州化学物理研究所 | 2023-12-01 | — | — | CN | claimed |
| CN-122011026-A | Asymmetric bidentate phosphine ligand and synthesis method thereof | 淮北师范大学 | 2026-05-12 | — | — | CN | disclosed |
| CN-122010810-A | The method comprises the following steps of18F-marked difluoromethyl seleno ether compound, and synthetic method and application thereof | 江苏省原子医学研究所 | 2026-05-12 | — | — | CN | disclosed |
| US-20260055128-A1 | ORGANONICKEL INTERMEDIATES USEFUL FOR CARBOXYLATION OF SUBSTRATES WITH CARBON DIOXIDE | U.S. DEPARTMENT OF ENERGY | 2026-02-26 | — | — | US | disclosed |
| US-12365678-B2 | Pharmaceutical process for the preparation of 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-((R)-S-methylsulfonimidoyl) cyclopropyl]pyrimidin-2-yl}-1H-pyrrolo[2,3-b] pyridine and intermediates | ASTRAZENECA AB (SE) | 2025-07-22 | — | — | US | disclosed |
| US-20170179399-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | US | disclosed |
| EP-2699641-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20140231715-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2014-08-21 | — | — | US | disclosed |
| US-20140231715-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2014-08-21 | — | — | US | disclosed |
| WO-2012143079-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365678-B2 | Pharmaceutical process for the preparation of 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-((R)-S-methylsulfonimidoyl) cyclopropyl]pyrimidin-2-yl}-1H-pyrrolo[2,3-b] pyridine and intermediates | TPMT, CYP3A7, HTR7 | MAPT 2037/4885TSHR 1434/4885LMNA 4609/4885 |
| US-20170179399-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2C19, CYP1B1, CYP2C9 | MAPT 2868/4885TSHR 3743/4885LMNA 3443/4885 |
| US-20260055128-A1 | ORGANONICKEL INTERMEDIATES USEFUL FOR CARBOXYLATION OF SUBSTRATES WITH CARBON DIOXIDE | MT-CO2, SCO2, ACACA | MAPT 3729/4885TSHR 4322/4885LMNA 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.