Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207546 | 1.00 | MAOB (0.37) | MAOBDPP4MT-CO2PTGS2PTGS1 | |
| SCHEMBL16216397 | 0.81 | AAK1 (0.37) | MT-CO2PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL16207402 | 0.81 | AAK1 (0.37) | MT-CO2PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL16216371 | 0.80 | MT-CO2 (0.40) | MAOBMT-CO2PTGS2PTGS1MEN1 | |
| SCHEMBL16207548 | 0.80 | MT-CO2 (0.40) | MAOBMT-CO2PTGS2PTGS1MEN1 | |
| SCHEMBL16219341 | 0.79 | PTGS1 (0.44) | PTGS2PTGS1MEN1KMT2ATSHR | |
| SCHEMBL16207491 | 0.79 | PTGS1 (0.44) | PTGS2PTGS1MEN1KMT2ATSHR | |
| SCHEMBL16207626 | 0.78 | MT-CO2 (0.35) | MAOBMT-CO2PTGS2PTGS1MEN1 | |
| SCHEMBL16216459 | 0.78 | MT-CO2 (0.35) | MAOBMT-CO2PTGS2PTGS1MEN1 | |
| SCHEMBL16216369 | 0.76 | MAOB (0.35) | MAOBDPP4MT-CO2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799424-B1 | 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE | LTT BIO PHARMA CO LTD (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | FPR1, OPRK1, FPR2 | MAOB 1824/4885DPP4 613/4885MT-CO2 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.