SCHEMBL16217693

SCHEMBL16217693

C=C(C(=O)OCC)C(=O)OCCCCCCOC(=O)C(=C)C(=O)OCC

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
ALDH1A1 P00352 4/20 0.46
MAPT P10636 1/20 0.46
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
THRB P10828 1/20 0.44
NAAA Q02083 1/20 0.42
CYP3A4 P08684 1/20 0.40
EPHX1 P07099 1/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ACHE P22303 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18499278 1.00 TSHR (0.57) TSHRALDH1A1MAPTRAD52NPSR1
SCHEMBL16217695 1.00 TSHR (0.57) TSHRALDH1A1MAPTRAD52NPSR1
SCHEMBL16217704 1.00 TSHR (0.57) TSHRALDH1A1MAPTRAD52NPSR1
SCHEMBL16217694 1.00 TSHR (0.57) TSHRALDH1A1MAPTRAD52NPSR1
SCHEMBL14886410 0.98 TSHR (0.53) TSHRALDH1A1MAPTRAD52NPSR1
SCHEMBL18499281 0.94 TSHR (0.56) TSHRALDH1A1MAPTRAD52NPSR1
SCHEMBL21802368 0.94 TSHR (0.67) TSHRALDH1A1RAD52NPSR1NAAA
SCHEMBL16736012 0.94 TSHR (0.67) TSHRALDH1A1RAD52NPSR1NAAA
SCHEMBL17973526 0.92 TSHR (0.50) TSHRALDH1A1MAPTRAD52NPSR1
SCHEMBL19184682 0.92 TSHR (0.50) TSHRALDH1A1MAPTRAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848402-A1 INK AND COATING FORMULATIONS AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME Sirrus, Inc. (US) 2021-07-14 EP disclosed
US-20210179892-A1 COMPOSITE AND LAMINATE ARTICLES AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME SIRRUS INC (US) 2021-06-17 US disclosed
US-10913875-B2 Composite and laminate articles and polymerizable systems for producing the same SIRRUS, INC. (US) 2021-02-09 US disclosed
US-10894856-B2 Polyurethane-vinyl hybrid polymers, methods of making them and their use BASF SE (DE) 2021-01-19 US disclosed
US-10611861-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed thereform NIPPON SHOKUBAI CO., LTD. (JP) 2020-04-07 US disclosed
US-10604601-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed therefrom SIRRUS, INC. (US) 2020-03-31 US disclosed
EP-3626784-A1 INK AND COATING FORMULATIONS AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME Sirrus, Inc. (US) 2020-03-25 EP disclosed
WO-2019195366-A1 HETEROGENEOUS CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS SIRRUS, INC. (US) 2019-10-10 WO disclosed
US-20190256639-A1 POLYURETHANE-VINYL HYBRID POLYMERS, METHODS OF MAKING THEM AND THEIR USE BASF SE (DE) 2019-08-22 US disclosed
US-20180222839-A1 HETEROGENEOUS CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS SIRRUS, INC. 2018-08-09 US disclosed
US-9181365-B2 Methods for activating polymerizable compositions, polymerizable systems, and products formed thereby SIRRUS, INC. (US) 2015-11-10 US disclosed
US-9181365-B2 Methods for activating polymerizable compositions, polymerizable systems, and products formed thereby SIRRUS, INC. (US) 2015-11-10 US disclosed
US-20150104660-A1 INK COATING FORMULATIONS AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME SIRRUS, INC. (US) 2015-04-16 US disclosed
US-20150104660-A1 INK COATING FORMULATIONS AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME SIRRUS, INC. (US) 2015-04-16 US disclosed
US-20150073110-A1 METHODS FOR ACTIVATING POLYMERIZABLE COMPOSITIONS, POLYMERIZABLE SYSTEMS, AND PRODUCTS FORMED THEREBY NIPPON SHOKUBAI CO., LTD. (JP) 2015-03-12 US disclosed
US-20150073110-A1 METHODS FOR ACTIVATING POLYMERIZABLE COMPOSITIONS, POLYMERIZABLE SYSTEMS, AND PRODUCTS FORMED THEREBY NIPPON SHOKUBAI CO., LTD. (JP) 2015-03-12 US disclosed
US-20150056879-A1 COMPOSITE AND LAMINATE ARTICLES AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME NIPPON SHOKUBAI CO., LTD. (JP) 2015-02-26 US disclosed
US-20150056879-A1 COMPOSITE AND LAMINATE ARTICLES AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME NIPPON SHOKUBAI CO., LTD. (JP) 2015-02-26 US disclosed
US-20140329980-A1 MULTIFUNCTIONAL MONOMERS, METHODS FOR MAKING MULTIFUNCTIONAL MONOMERS, POLYMERIZABLE COMPOSTIONS AND PRODUCTS FORMED THEREFORM SIRRUS, INC. 2014-11-06 US disclosed
US-20140329980-A1 MULTIFUNCTIONAL MONOMERS, METHODS FOR MAKING MULTIFUNCTIONAL MONOMERS, POLYMERIZABLE COMPOSTIONS AND PRODUCTS FORMED THEREFORM SIRRUS, INC. 2014-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10604601-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed therefrom BHMT2, MACF1, BHMT TSHR 4885/4885ALDH1A1 560/4885MAPT 996/4885
US-20140329980-A1 MULTIFUNCTIONAL MONOMERS, METHODS FOR MAKING MULTIFUNCTIONAL MONOMERS, POLYMERIZABLE COMPOSTIONS AND PRODUCTS FORMED THEREFORM BHMT2, MTHFD2, BHMT TSHR 4885/4885ALDH1A1 601/4885MAPT 851/4885
US-20180222839-A1 HETEROGENEOUS CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS NOTUM, CES1, ADH5 TSHR 2652/4885ALDH1A1 137/4885MAPT 3780/4885
US-10611861-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed thereform MACF1, BHMT2, MTHFD2 TSHR 4885/4885ALDH1A1 531/4885MAPT 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.