Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | TCF4 | P15884 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16218479 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL4884781 | 0.75 | KMT2A (0.63) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL14315202 | 0.75 | ALDH1A1 (1.00) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL14181874 | 0.75 | ALDH1A1 (0.56) | KMT2AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL16221729 | 0.73 | ALDH1A1 (1.00) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL14325640 | 0.73 | RAB9A (0.68) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL18539182 | 0.72 | ALDH1A1 (1.00) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL13446980 | 0.72 | ALDH1A1 (1.00) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL14901826 | 0.72 | MAPT (0.66) | KMT2AALDH1A1KDM4EHPGDPKM | |
| SCHEMBL14305788 | 0.72 | KMT2A (0.76) | KMT2AALDH1A1KDM4EHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486447-B2 | Compositions and methods for controlling neuronal excitation | THE GENERAL HOSPITAL CORPORATION (US) | 2016-11-08 | — | — | US | disclosed |
| US-20140330195-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330195-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION | TRPA1, TRPV1, HCN3 | KMT2A 3166/4885ALDH1A1 989/4885KDM4E 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.