SCHEMBL16219632

SCHEMBL16219632

CC1(C)c2cc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)ccc2-c2c1cc(N(c1ccccc1)c1ccccc1)c1ccccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16219673 0.99 PDK2 (0.32) PDK2
SCHEMBL17153676 0.96 PDK2 (0.33) RXRARXRBPDK2
SCHEMBL24236385 0.94
SCHEMBL16219626 0.93 PDK2 (0.34) PDK2
SCHEMBL18267060 0.93 BRD4 (0.30)
SCHEMBL24236215 0.92 RXRA (0.30) RXRARXRB
SCHEMBL16219660 0.92 LPL (0.31)
SCHEMBL16219672 0.92 LPL (0.31)
SCHEMBL16219664 0.91 PDK2 (0.31) PDK2
SCHEMBL15491026 0.91 ALDH1A1 (0.32) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220140247-A1 PLURALITY OF HOST MATERIALS, COMPOSITION COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-05-05 US disclosed
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-02-03 US disclosed
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, EML4, NECTIN4 RXRA 2922/4885RXRB 3578/4885PDK2 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.