Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16220184 | 0.86 | KMT2A (0.49) | KMT2AALDH1A1CA2CA12CA9 | |
| SCHEMBL11842004 | 0.84 | KMT2A (0.61) | KMT2AALDH1A1CA2CA12CA9 | |
| SCHEMBL28098231 | 0.83 | KMT2A (0.50) | KMT2AALDH1A1CA2CA12CA9 | |
| SCHEMBL4752052 | 0.83 | KMT2A (0.50) | KMT2AALDH1A1CA2CA12CA9 | |
| SCHEMBL28143438 | 0.81 | KMT2A (0.53) | KMT2AALDH1A1MAPTHTTTSHR | |
| SCHEMBL709683 | 0.81 | TSHR (0.62) | KMT2AALDH1A1HTTTSHRMEN1 | |
| SCHEMBL11763133 | 0.80 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPTHTTTSHR | |
| SCHEMBL11226703 | 0.78 | KMT2A (0.80) | KMT2AALDH1A1CA2CA12CA9 | |
| SCHEMBL5879758 | 0.78 | CYP2C9 (0.55) | KMT2AALDH1A1MAPTHTTTSHR | |
| SCHEMBL3166437 | 0.78 | HTT (0.47) | KMT2AALDH1A1MAPTCA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771324-B1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | UNIV EMORY (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9499489-B2 | Myxovirus therapeutics, compounds, and uses related thereto | EMORY UNIVERSITY (US) | 2016-11-22 | — | — | US | disclosed |
| US-20140329817-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | CHILDREN'S HEATLHCARE OF ATLANTA, INC. (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329817-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | RPP30, RNASE1, MAVS | KMT2A 3295/4885ALDH1A1 1520/4885MAPT 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.