Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16220186 | 0.86 | KMT2A (0.50) | KMT2ACA2CA12CA9CA1 | |
| SCHEMBL11842004 | 0.83 | KMT2A (0.61) | KMT2ACA2CA12CA9CA1 | |
| SCHEMBL26615292 | 0.81 | TSHR (0.61) | KMT2ACA2CA12CA9CA1 | |
| SCHEMBL11131291 | 0.79 | GAA (0.50) | KMT2AHTTTSHRMEN1HSD11B1 | |
| SCHEMBL1396538 | 0.77 | ALDH1A1 (0.44) | KMT2ACA2CA12CA9CA1 | |
| SCHEMBL11226703 | 0.77 | KMT2A (0.80) | KMT2ACA2CA12CA9CA1 | |
| SCHEMBL2927995 | 0.76 | KMT2A (0.42) | KMT2ACA2CA12CA9AGTR1 | |
| SCHEMBL20379453 | 0.76 | KMT2A (0.57) | KMT2ACA2CA12CA9CA1 | |
| SCHEMBL11219216 | 0.76 | HTR6 (0.65) | KMT2ACA2CA12CA9CA1 | |
| SCHEMBL27413429 | 0.76 | HTR7 (0.46) | KMT2AMEN1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771324-B1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | UNIV EMORY (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9499489-B2 | Myxovirus therapeutics, compounds, and uses related thereto | EMORY UNIVERSITY (US) | 2016-11-22 | — | — | US | disclosed |
| CN-104000805-B | Styryl-sulfamide compound is preparing the application in anti-HIV-1 virus drugs | Guangzhou Zhongheng Electronic Technology Co.,Ltd. (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-104000805-B | Styryl-sulfamide compound is preparing the application in anti-HIV-1 virus drugs | Guangzhou Zhongheng Electronic Technology Co.,Ltd. (CN) | 2016-03-02 | — | — | CN | disclosed |
| US-20140329817-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | CHILDREN'S HEATLHCARE OF ATLANTA, INC. (US) | 2014-11-06 | — | — | US | disclosed |
| CN-104000805-A | Application of styryl-sulfonamide compounds to preparation of HIV-1 (Human Immunodeficiency Virus-1)-resistant drugs | UNIV SUN YAT SEN | 2014-08-27 | — | — | CN | disclosed |
| CN-104000805-A | Application of styryl-sulfonamide compounds to preparation of HIV-1 (Human Immunodeficiency Virus-1)-resistant drugs | UNIV SUN YAT SEN | 2014-08-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329817-A1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | RPP30, RNASE1, MAVS | KMT2A 3295/4885CA2 3096/4885CA12 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.