SCHEMBL162243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL71518	0.86	NPSR1 (0.59)	L3MBTL1NPSR1KDM4EALDH1A1KDM4C
	SCHEMBL9632764	0.80	NPSR1 (0.52)	L3MBTL1NPSR1KDM4EALDH1A1KDM4C
	SCHEMBL31027302	0.78	KDM4E (0.58)	L3MBTL1NPSR1KDM4EALDH1A1KDM4C
	SCHEMBL29409978	0.78	NPSR1 (0.50)	L3MBTL1NPSR1KDM4EALDH1A1KDM4C
	SCHEMBL361255	0.78	KDM4E (0.58)	L3MBTL1NPSR1KDM4EALDH1A1KDM4C
	SCHEMBL871602	0.78	NPSR1 (0.50)	L3MBTL1NPSR1KDM4EALDH1A1KDM4C
	SCHEMBL360639	0.78	NPSR1 (0.50)	L3MBTL1NPSR1KDM4EALDH1A1KDM4C
	SCHEMBL162744	0.78	ALDH1A1 (0.37)	L3MBTL1NPSR1ALDH1A1
	SCHEMBL162731	0.78	CA12 (0.40)	NPSR1KDM4EALDH1A1MAPT
	SCHEMBL159285	0.78	BRD4 (0.50)	L3MBTL1NPSR1KDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.