SCHEMBL871602

SCHEMBL871602

COC(=O)c1nccnc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
KDM4E B2RXH2 6/20 0.42
KDM4C Q9H3R0 2/20 0.41
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA7 P43166 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
LMNA P02545 2/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
NFKB1 P19838 1/20 0.38
XDH P47989 1/20 0.38
GFER P55789 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
FUT7 Q11130 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71518 0.86 NPSR1 (0.59) NPSR1L3MBTL1KDM4EKDM4CCA12
SCHEMBL9632764 0.80 NPSR1 (0.52) NPSR1L3MBTL1KDM4EKDM4CGAA
SCHEMBL28150097 0.78 L3MBTL1 (0.30) L3MBTL1
SCHEMBL29409978 0.78 NPSR1 (0.50) NPSR1L3MBTL1KDM4EKDM4CTDP1
SCHEMBL361255 0.78 KDM4E (0.58) NPSR1L3MBTL1KDM4EKDM4CALDH1A1
SCHEMBL360639 0.78 NPSR1 (0.50) NPSR1L3MBTL1KDM4EKDM4CTDP1
SCHEMBL162243 0.78 L3MBTL1 (0.53) NPSR1L3MBTL1KDM4EKDM4CGAA
SCHEMBL31027302 0.78 KDM4E (0.58) NPSR1L3MBTL1KDM4EKDM4CALDH1A1
SCHEMBL23888774 0.77 NPSR1 (0.48) NPSR1L3MBTL1KDM4EKDM4CALDH1A1
SCHEMBL261104 0.77 NPSR1 (0.48) NPSR1L3MBTL1KDM4EGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108067191-A For the reactor assembly of orthophosphates in Adsorption waste water 北京益清源环保科技有限公司 2018-05-25 CN claimed
CN-108031441-A There is the modified activated carbon absorbent of absorption property to the orthophosphates in water body 北京益清源环保科技有限公司 2018-05-15 CN claimed
CN-105732524-A A preparing method of 6-bromo-3-hydroxy-2-pyrazinamide 青岛市黄岛区中医医院 2016-07-06 CN claimed
CN-102775358-B Preparation method of 6-fluoro-3-hydroxy-2-pyrazinamide SHANDONG QIDU PHARMACEUTICAL 2015-05-27 CN claimed
CN-102603657-B Preparation method of 6-bromine-3-hydroxyl-2-pyrazinamide SHANDONG QIDU PHARMACEUTICAL 2015-02-04 CN claimed
CN-102775358-A Preparation method of 6-fluoro-3-hydroxy-2-pyrazinamide SHANDONG QIDU PHARMACEUTICAL 2012-11-14 CN claimed
CN-102603657-A Preparation method of 6-bromine-3-hydroxyl-2-pyrazinamide SHANDONG QIDU PHARMACEUTICAL 2012-07-25 CN claimed
US-20260138991-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS INC (US) 2026-05-21 US disclosed
EP-4705298-A2 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES Moma Therapeutics, Inc. (US) 2026-03-11 EP disclosed
US-12559508-B2 Semi-saturated bicyclic derivatives and related uses MOMA THERAPEUTICS, INC. (US) 2026-02-24 US disclosed
US-20250230171-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2025-07-17 US disclosed
WO-2024211836-A2 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. (US) 2024-10-10 WO disclosed
US-20240148732-A1 TRICYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISORDERS SCHRÖDINGER, INC. 2024-05-09 US disclosed
CN-1539828-A Nitrogen-contg. heterocyclic carboxamide derivatives or salt thereof ��ɽ��ѧ��ҵ��ʽ���� 2004-10-27 CN disclosed
US-6787544-B2 USEFUL FOR PROPHYLAXIS AND THERAPY OF VIRUS INFECTIONS AND ESPECIALLY INFLUENZA VIRUS INFECTIONS TOYAMA CHEMICAL CO., LTD. (JP) 2004-09-07 US disclosed
CN-1154493-C Nitrogen-containing heterocyclic carboxamide derivative or salt thereof and antiviral agent containing the same ��ɽ��ѧ��ҵ��ʽ���� 2004-06-23 CN disclosed
EP-1417967-A1 NOVEL VIRUS PROLIFERATION INHIBITION/VIRUCIDAL METHOD AND NOVEL PYRADINE NUCLEOTIDE/PYRADINE NUCLEOSIDE ANALOGUE TOYAMA CHEMICAL CO., LTD. (JP) 2004-05-12 EP disclosed
US-20020013316-A1 Nitrogen-containing heterocyclic carboxamide derivatives or salts thereof and antiviral agents comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 2002-01-31 US disclosed
CN-1313768-A Nitrogen-containing heterocyclic carboxamide derivative or salt thereof and antiviral agent containing the same TOYAMA CHEMICAL CO LTD (JP) 2001-09-19 CN disclosed
EP-1112743-A1 NITROGENOUS HETEROCYCLIC CARBOXAMIDE DERIVATIVES OR SALTS THEREOF AND ANTIVIRAL AGENTS CONTAINING BOTH TOYAMA CHEMICAL CO., LTD. (JP) 2001-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148732-A1 TRICYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISORDERS MALT1, LITAF, IL2 NPSR1 2968/4885L3MBTL1 4811/4885KDM4E 3981/4885
US-20250230171-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES POLQ, POLB, POLK NPSR1 3684/4885L3MBTL1 3878/4885KDM4E 2459/4885
US-20260138991-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES POLA1, SUB1, CTDSP1 NPSR1 2254/4885L3MBTL1 1344/4885KDM4E 4515/4885
US-12559508-B2 Semi-saturated bicyclic derivatives and related uses POLA1, CTDSP1, SUB1 NPSR1 2680/4885L3MBTL1 1625/4885KDM4E 4522/4885
US-20020013316-A1 Nitrogen-containing heterocyclic carboxamide derivatives or salts thereof and antiviral agents comprising the same ZC3HAV1, EIF2AK2, NSUN2 NPSR1 1408/4885L3MBTL1 992/4885KDM4E 626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.