Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.49 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846753 | 0.79 | NPC1 (0.38) | ESR1ESR2POLBMAPTGAA | |
| SCHEMBL6547698 | 0.77 | ESR1 (0.75) | ESR1ESR2NPFFR1NPFFR2MAPT | |
| SCHEMBL16229878 | 0.77 | ESR1 (0.46) | ESR1ESR2NPFFR1NPFFR2GAA | |
| SCHEMBL8356086 | 0.76 | NPC1 (0.41) | ESR1ESR2POLBMAPTGAA | |
| SCHEMBL8358341 | 0.76 | SIGMAR1 (0.50) | ESR1ESR2POLBMAPTGAA | |
| SCHEMBL21995977 | 0.76 | ESR1 (0.45) | ESR1ESR2NPFFR1NPFFR2MAPT | |
| SCHEMBL11881551 | 0.74 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7927948 | 0.73 | PTGDR2 (0.39) | ESR1ESR2POLBMAPTGAA | |
| SCHEMBL29226313 | 0.73 | KDM1A (0.33) | ESR1ESR2POLBMAPTGAA | |
| SCHEMBL27191888 | 0.72 | PLG (0.42) | ESR1ESR2GAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2017-10-26 | — | — | US | disclosed |
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2017-10-26 | — | — | US | disclosed |
| US-9738663-B2 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | EUTICALS S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| US-9738663-B2 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | EUTICALS S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| EP-2994473-B1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | EUTICALS SPA (IT) | 2016-12-21 | — | — | EP | disclosed |
| US-20160075723-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2016-03-17 | — | — | US | disclosed |
| EP-2801577-A1 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | Euticals S.P.A. (IT) | 2014-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AADAT, BCAT2, BCAT1 | ESR1 1272/4885ESR2 1338/4885NPFFR1 1403/4885 |
| US-20160075723-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AADAT, BCAT2, BCAT1 | ESR1 1900/4885ESR2 2049/4885NPFFR1 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.