Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.79 |
| ▸ | CTSS | P25774 | 6/20 | 0.79 |
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
| ▸ | TYRO3 | Q06418 | 11/20 | 0.62 |
| ▸ | MERTK | Q12866 | 6/20 | 0.55 |
| ▸ | FLT3 | P36888 | 4/20 | 0.55 |
| ▸ | GAS6 | Q14393 | 4/20 | 0.55 |
| ▸ | AXL | P30530 | 3/20 | 0.49 |
| ▸ | SELP | P16109 | 2/20 | 0.49 |
| ▸ | SPR | P35270 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16231092 | 0.89 | CTSL (0.77) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16231105 | 0.89 | CTSS (0.62) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16232057 | 0.88 | CTSS (1.00) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16231082 | 0.87 | CTSS (0.74) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16231098 | 0.83 | CTSS (0.62) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16231084 | 0.78 | CTSK (0.76) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16232056 | 0.77 | CTSS (1.00) | CTSLCTSSCTSKTYRO3 | |
| SCHEMBL16231088 | 0.76 | CTSL (0.79) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16231086 | 0.76 | CTSL (0.79) | CTSLCTSSCTSKTYRO3MERTK | |
| SCHEMBL16232238 | 0.73 | CTSS (1.00) | CTSLCTSSCTSKTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336503-A1 | RADIOLABELED BIOMARKERS FOR OSTEOCLAST ACTIVATION AND RELATED METHODS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336503-A1 | RADIOLABELED BIOMARKERS FOR OSTEOCLAST ACTIVATION AND RELATED METHODS THEREOF | CTSK, CTSF, CTSB | CTSL 11/4885CTSS 7/4885CTSK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.