SCHEMBL16233232

SCHEMBL16233232

COc1cc(C(=O)NCC2(N3CCN(C)CC3)CCCCC2)cc(OC)c1OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 4/20 0.70
HCN1 O60741 5/20 0.64
HCN4 Q9Y3Q4 5/20 0.64
TP53 P04637 3/20 0.64
OPRM1 P35372 1/20 0.56
SIGMAR1 Q99720 1/20 0.56
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
NPC1 O15118 1/20 0.53
GAA P10253 1/20 0.52
ALDH1A1 P00352 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16233170 0.91 SLC6A5 (0.61) SLC6A5HCN1HCN4TP53ALDH1A1
SCHEMBL16233224 0.89 HCN1 (0.61) SLC6A5HCN1HCN4TP53OPRM1
SCHEMBL16233235 0.84 SLC6A5 (0.62) SLC6A5HCN1HCN4ALDH1A1L3MBTL1
SCHEMBL16233161 0.84 SLC6A5 (0.87) SLC6A5HCN1HCN4TP53CRHBP
SCHEMBL16233192 0.84 TP53 (0.73) HCN1HCN4TP53OPRM1SIGMAR1
SCHEMBL5022643 0.83 SLC6A5 (1.00) SLC6A5TP53OPRM1L3MBTL1
SCHEMBL16233159 0.83 SLC6A5 (0.78) SLC6A5TP53L3MBTL1
SCHEMBL5017542 0.82 SLC6A5 (1.00) SLC6A5TP53L3MBTL1
Hydrochloric Acid SCHEMBL26654518 0.81 SLC6A5 (1.00) SLC6A5TP53L3MBTL1
SCHEMBL16233193 0.80 HCN1 (0.53) SLC6A5HCN1HCN4TP53OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF TRPV1, TRPA1, TRPV5 SLC6A5 1714/4885HCN1 253/4885HCN4 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.