SCHEMBL16233192

SCHEMBL16233192

CN1CCN(C2(CNC(=O)c3ccc(OCc4ccccc4)cc3)CCCCC2)CC1

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.73
LMNA P02545 3/20 0.61
THRB P10828 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
OPRM1 P35372 2/20 0.61
SIGMAR1 Q99720 2/20 0.61
HCN1 O60741 6/20 0.59
HCN4 Q9Y3Q4 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16510718 0.91 TP53 (0.66) TP53LMNATHRBMEN1KMT2A
SCHEMBL16233178 0.90 TP53 (0.60) TP53LMNATHRBMEN1KMT2A
SCHEMBL16233224 0.85 HCN1 (0.61) TP53LMNATHRBMEN1KMT2A
SCHEMBL14835994 0.85 SLC6A9 (0.78) TP53
Hydrochloric Acid SCHEMBL16496619 0.85 SLC6A9 (0.77) TP53
SCHEMBL16233241 0.85 TP53 (1.00) TP53LMNATHRBMEN1KMT2A
SCHEMBL16233232 0.84 SLC6A5 (0.70) TP53OPRM1SIGMAR1HCN1HCN4
SCHEMBL16233227 0.82 MEN1 (0.57) TP53LMNAMEN1KMT2AHCN1
SCHEMBL16233199 0.82 LMNA (0.56) TP53LMNATHRBMEN1KMT2A
SCHEMBL16233240 0.80 PARP10 (0.53) LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF TRPV1, TRPA1, TRPV5 TP53 4562/4885LMNA 3607/4885THRB 4691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.