SCHEMBL16233241

SCHEMBL16233241

CCCCOc1ccc(C(=O)NCC2(N3CCN(C)CC3)CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 1.00
SLC6A5 Q9Y345 2/20 0.66
LMNA P02545 3/20 0.64
THRB P10828 2/20 0.64
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
CRHBP P24387 2/20 0.63
CRHR2 Q13324 2/20 0.63
GAA P10253 1/20 0.61
HCN1 O60741 2/20 0.59
HCN4 Q9Y3Q4 2/20 0.59
OPRM1 P35372 1/20 0.58
SIGMAR1 Q99720 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SLC6A9 P48067 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16233200 0.90 TP53 (0.81) TP53SLC6A5LMNATHRBMEN1
SCHEMBL16233192 0.85 TP53 (0.73) TP53LMNATHRBMEN1KMT2A
SCHEMBL16234613 0.82 TP53 (0.69) TP53SLC6A5LMNATHRBMEN1
SCHEMBL5017430 0.80 SLC6A5 (1.00) TP53SLC6A5LMNATHRBCRHBP
SCHEMBL16510718 0.79 TP53 (0.66) TP53LMNATHRBMEN1KMT2A
SCHEMBL14836309 0.76 SLC6A9 (0.80) TP53MEN1KMT2ASLC6A9
SCHEMBL14836364 0.76 SLC6A9 (0.80) TP53MEN1KMT2ASLC6A9
Hydrochloric Acid SCHEMBL16496729 0.75 SLC6A9 (0.78) TP53MEN1KMT2ASLC6A9
Hydrochloric Acid SCHEMBL16497154 0.75 SLC6A9 (0.78) TP53MEN1KMT2ASLC6A9
SCHEMBL14835994 0.75 SLC6A9 (0.78) TP53SLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF TRPV1, TRPA1, TRPV5 TP53 4562/4885SLC6A5 1714/4885LMNA 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.