Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234873 | 0.84 | ALDH1A1 (0.61) | LMNAALDH1A1SMN1; SMN2KMT2AHSP90AA1 | |
| SCHEMBL16235049 | 0.83 | TRPA1 (0.50) | LMNAALDH1A1KMT2ACA12CES2 | |
| SCHEMBL20445881 | 0.82 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2KMT2AHSP90AA1 | |
| SCHEMBL23544612 | 0.79 | CES2 (0.52) | LMNAALDH1A1SMN1; SMN2KMT2ACA12 | |
| SCHEMBL16235318 | 0.79 | GSK3B (0.51) | ALDH1A1KMT2AMEN1CA1CA2 | |
| SCHEMBL11633473 | 0.78 | CES2 (0.46) | LMNAALDH1A1SMN1; SMN2KMT2AHSP90AA1 | |
| SCHEMBL1983194 | 0.78 | CES2 (0.46) | LMNAALDH1A1SMN1; SMN2KMT2AHSP90AA1 | |
| SCHEMBL15111219 | 0.77 | ALDH1A1 (0.41) | LMNAALDH1A1SMN1; SMN2KMT2AHSP90AA1 | |
| SCHEMBL15254610 | 0.75 | CYP1A2 (0.52) | LMNAALDH1A1SMN1; SMN2FPR2FPR1 | |
| SCHEMBL1440635 | 0.75 | KMT2A (0.43) | LMNAALDH1A1SMN1; SMN2KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014184235-A1 | BENZAMIDE TRPA1 ANTAGONISTS | Acturum Life Science AB (SE) | 2014-11-20 | — | — | WO | disclosed |