Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235114 | 0.73 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL16235266 | 0.71 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL16235648 | 0.70 | S100A9 (0.33) | — | |
| SCHEMBL16235142 | 0.69 | GPBAR1 (0.34) | ALDH1A1 | |
| SCHEMBL16235321 | 0.69 | ACLY (0.33) | ALDH1A1 | |
| SCHEMBL16235405 | 0.69 | GPBAR1 (0.37) | ALDH1A1 | |
| SCHEMBL16235265 | 0.68 | ACLY (0.47) | ALDH1A1 | |
| SCHEMBL16235741 | 0.68 | CCR4 (0.33) | ALDH1A1 | |
| SCHEMBL16235683 | 0.68 | S100A9 (0.40) | ALDH1A1 | |
| SCHEMBL16235517 | 0.67 | ACLY (0.44) | ALDH1A1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | claimed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | claimed |