Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 3/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235265 | 0.80 | ACLY (0.47) | ACLYALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16236114 | 0.75 | FABP4 (0.40) | ACLYFABP4DDR1HSD11B1MEN1 | |
| SCHEMBL16235545 | 0.71 | HSD11B1 (0.46) | ALDH1A1HSD11B1MEN1KMT2A | |
| SCHEMBL16235650 | 0.71 | S100A9 (0.39) | ACLYFABP4MEN1KMT2AITGB1 | |
| SCHEMBL16235684 | 0.69 | S100A9 (0.40) | ACLYALDH1A1FABP4HSD11B1MEN1 | |
| SCHEMBL16235401 | 0.68 | FABP4 (0.39) | ACLYFABP4HSD11B1MEN1KMT2A | |
| SCHEMBL16235513 | 0.68 | S100A9 (0.47) | ACLYALDH1A1HPGD | |
| SCHEMBL16234972 | 0.68 | RAB9A (0.40) | ACLYALDH1A1FABP4MAPK1 | |
| SCHEMBL16235515 | 0.67 | ALDH1A1 (0.30) | ALDH1A1DDR1 | |
| SCHEMBL16235298 | 0.66 | FABP4 (0.41) | ACLYFABP4HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | claimed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | claimed |