Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Benzylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 10/20 | 0.46 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylimidazole SCHEMBL339106 | 0.98 | ALDH1A1 (0.46) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL1123480 | 0.96 | ALDH1A1 (0.49) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL3786784 | 0.96 | ALDH1A1 (0.44) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL16699274 | 0.88 | ALDH1A1 (0.47) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL16237033 | 0.88 | FDPS (0.43) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL3418783 | 0.88 | ALDH1A1 (0.46) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL16237353 | 0.86 | ALDH1A1 (0.41) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL7942344 | 0.86 | ALDH1A1 (0.41) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL28855087 | 0.85 | NPSR1 (0.40) | CHKAALDH1A1LMNAHTTSMN1; SMN2 | |
| Benzylimidazole SCHEMBL16236716 | 0.85 | ALDH1A1 (0.41) | CHKAALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604897-B2 | Ionic liquid composition | RELIANCE INDUSTRIES LIMITED (IN) | 2017-03-28 | — | — | US | disclosed |
| US-20160107972-A1 | IONIC LIQUID COMPOSITION | RELIANCE INDUSTRIES LIMITED (IN) | 2016-04-21 | — | — | US | disclosed |
| EP-2997114-A2 | IONIC LIQUID COMPOSITION | Reliance Industries Limited (IN) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184804-A2 | IONIC LIQUID COMPOSITION | RELIANCE INDUSTRIES LIMITED (IN) | 2014-11-20 | — | — | WO | disclosed |