Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Benzylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylimidazole SCHEMBL1123480 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL339106 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL16237306 | 0.86 | CHKA (0.46) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL3786784 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL3418783 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL16237033 | 0.82 | FDPS (0.43) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL16699274 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL16237353 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL16236716 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzylimidazole SCHEMBL16700264 | 0.77 | LMNA (0.37) | ALDH1A1KDM4ERAB9ALMNACHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094706-A1 | PROCESS FOR THE BIOCIDAL TREATMENT OF SURFACES | RHODIA CHIMIE (FR) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002449-A1 | PROCESS FOR THE BIOCIDAL TREATMENT OF SURFACES | RHODIA CHIMIE (FR) | 2000-01-20 | — | — | WO | disclosed |