Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Benzylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 known ✓ | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 known ✓ | P35462 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylimidazole SCHEMBL339106 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL16700264 | 0.86 | LMNA (0.37) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL16237306 | 0.86 | CHKA (0.46) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL1123480 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL3786784 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL16236716 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL16699274 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL16237033 | 0.85 | FDPS (0.43) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL3418783 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzylimidazole SCHEMBL7942344 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAB9ACHKALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3244987-B1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2022-06-22 | — | — | EP | claimed |
| EP-3244987-A1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | Chevron Phillips Chemical Company LP (US) | 2017-11-22 | — | — | EP | claimed |
| US-20150133711-A1 | Separations With Ionic Liquid Solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2015-05-14 | — | — | US | claimed |
| EP-3244987-B1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2022-06-22 | — | — | EP | disclosed |
| US-10227274-B2 | Separations with ionic liquid solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2019-03-12 | — | — | US | disclosed |
| EP-3244987-A1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | Chevron Phillips Chemical Company LP (US) | 2017-11-22 | — | — | EP | disclosed |
| US-9604897-B2 | Ionic liquid composition | RELIANCE INDUSTRIES LIMITED (IN) | 2017-03-28 | — | — | US | disclosed |
| US-20160107972-A1 | IONIC LIQUID COMPOSITION | RELIANCE INDUSTRIES LIMITED (IN) | 2016-04-21 | — | — | US | disclosed |
| EP-2997114-A2 | IONIC LIQUID COMPOSITION | Reliance Industries Limited (IN) | 2016-03-23 | — | — | EP | disclosed |
| US-20150133711-A1 | Separations With Ionic Liquid Solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2015-05-14 | — | — | US | disclosed |
| WO-2014184804-A2 | IONIC LIQUID COMPOSITION | RELIANCE INDUSTRIES LIMITED (IN) | 2014-11-20 | — | — | WO | disclosed |