Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239989 | 0.87 | IMPDH2 (0.40) | BRD4KDM1AKMT2A | |
| SCHEMBL16239497 | 0.87 | L3MBTL1 (0.43) | BRD4KMT2A | |
| SCHEMBL16239598 | 0.87 | KMT2A (0.39) | KMT2A | |
| SCHEMBL16239646 | 0.86 | BRD4 (0.40) | BRD4KMT2ACASP3NLRP3 | |
| SCHEMBL16239481 | 0.86 | BRD4 (0.36) | BRD4KDM1A | |
| SCHEMBL16240123 | 0.85 | SLC22A12 (0.43) | BRD4SLC22A12CASP3NLRP3 | |
| SCHEMBL16240087 | 0.84 | GPR119 (0.41) | BRD4KMT2A | |
| SCHEMBL2135474 | 0.83 | BRD4 (0.42) | BRD4KMT2ASLC22A12CASP3NLRP3 | |
| SCHEMBL2134891 | 0.79 | BRD4 (0.44) | BRD4KMT2ACASP3NLRP3 | |
| SCHEMBL2136761 | 0.79 | BRD4 (0.43) | BRD4KMT2ACASP3NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630124-B1 | TETRAHYDROQUINOLINE DERIVATIVES USED AS AMPK ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | claimed |