Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 0.41 |
| ▸ | BCHE | P06276 | 11/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239528 | 0.89 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL2615612 | 0.86 | ACHE (0.34) | ACHEBCHEMRGPRX1 | |
| SCHEMBL2138954 | 0.86 | PRKAB2 (0.41) | — | |
| SCHEMBL16239846 | 0.85 | ALDH1A1 (0.38) | ACHEBCHE | |
| SCHEMBL16239475 | 0.85 | ALDH1A1 (0.39) | ACHEBCHE | |
| SCHEMBL16239500 | 0.84 | SLC10A2 (0.40) | ACHEBCHE | |
| SCHEMBL16239546 | 0.83 | USP2 (0.40) | ACHEBCHE | |
| SCHEMBL2141345 | 0.83 | HPGD (0.42) | MRGPRX1 | |
| SCHEMBL2133143 | 0.82 | MRGPRX1 (0.39) | MRGPRX1 | |
| SCHEMBL2135729 | 0.80 | PSIP1 (0.36) | MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630124-B1 | TETRAHYDROQUINOLINE DERIVATIVES USED AS AMPK ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | claimed |