Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 15/20 | 0.63 |
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | F13A1 | P00488 | 6/20 | 0.54 |
| ▸ | TGM1 | P22735 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16242097 | 0.85 | TGM2 (0.56) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL29718235 | 0.82 | TGM2 (0.61) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL30995086 | 0.81 | TGM2 (0.59) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL1132464 | 0.81 | THRA (0.67) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL10012411 | 0.81 | TGM2 (0.51) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL440756 | 0.80 | TGM2 (0.63) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL439369 | 0.80 | TGM2 (0.79) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL3150538 | 0.79 | SMN1; SMN2 (0.60) | LMNARAB9A | |
| SCHEMBL16685886 | 0.79 | SMN1; SMN2 (0.49) | LMNANPC1CASP3RAB9ASENP7 | |
| SCHEMBL16242100 | 0.79 | TGM2 (0.61) | TGM2THRATHRBF13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371459-A1 | INDUSTRIAL PROCESS FOR PREPARATION OF 1,2-DIHYDROQUINOLINE DERIVATIVE OR A SALT THEREOF, AND INTERMEDIATE FOR PREPARATION THEREOF | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2014-12-18 | — | — | US | disclosed |
| EP-2805948-A1 | INDUSTRIAL PROCESS FOR PREPARATION OF 1,2-DIHYDROQUINOLINE DERIVATIVE OR A SALT THEREOF, AND INTERMEDIATE FOR PREPARATION THEREOF | Santen Pharmaceutical Co., Ltd (JP) | 2014-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371459-A1 | INDUSTRIAL PROCESS FOR PREPARATION OF 1,2-DIHYDROQUINOLINE DERIVATIVE OR A SALT THEREOF, AND INTERMEDIATE FOR PREPARATION THEREOF | NR3C2, NR5A1, NR3C1 | TGM2 3844/4885THRA 1193/4885THRB 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.