Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 19/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | F13A1 | P00488 | 11/20 | 0.49 |
| ▸ | TGM1 | P22735 | 11/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16242098 | 0.81 | TGM2 (0.63) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL27632063 | 0.80 | TGM2 (0.64) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL16242097 | 0.80 | TGM2 (0.56) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL1132464 | 0.76 | THRA (0.67) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL10012411 | 0.76 | TGM2 (0.51) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL440756 | 0.76 | TGM2 (0.63) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL3375330 | 0.75 | CYP17A1 (0.53) | — | |
| SCHEMBL18314731 | 0.75 | TGM2 (0.59) | TGM2THRATHRBF13A1TGM1 | |
| SCHEMBL4952656 | 0.75 | CA2 (0.58) | LMNA | |
| SCHEMBL439369 | 0.75 | TGM2 (0.79) | TGM2THRATHRBF13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024156288-A1 | DNMT1 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | SHANGHAI KYGENT PHARMACEUTICAL CO., LTD (CN) | 2024-08-02 | — | — | WO | disclosed |