Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 8/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | GRK2 | P25098 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738956 | 1.00 | GPR52 (0.38) | GPR52MKNK1MKNK2CA1CA2 | |
| SCHEMBL30821160 | 0.93 | GPR52 (0.40) | GPR52MKNK1MKNK2CA1CA2 | |
| SCHEMBL30309306 | 0.91 | MKNK1 (0.36) | GPR52MKNK1MKNK2CA1CA2 | |
| SCHEMBL20492267 | 0.91 | MKNK1 (0.36) | GPR52MKNK1MKNK2CA1CA2 | |
| SCHEMBL363527 | 0.91 | CA1 (0.35) | CA1CA2RECQLKDM4ERXRA | |
| SCHEMBL20261758 | 0.91 | CA1 (0.35) | CA1CA2RECQLKDM4ERXRA | |
| SCHEMBL362701 | 0.91 | RXRB (0.41) | CA1CA2PDK2RECQLKDM4E | |
| SCHEMBL1694737 | 0.91 | CA1 (0.35) | CA1CA2APAF1POLBPABPC1 | |
| SCHEMBL2014009 | 0.91 | RXRB (0.41) | CA1CA2PDK2RECQLKDM4E | |
| SCHEMBL12274098 | 0.91 | RXRB (0.41) | CA1CA2PDK2RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10588317-B2 | Isoxazoline-substituted benzamides and analogues as insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-03-17 | — | — | US | disclosed |
| US-20180255780-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-13 | — | — | US | disclosed |
| US-9126995-B2 | Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20140350261-A1 | METHOD FOR CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE ISOXAZOLINE COMPOUND, AND OPTICALLY ACTIVE ISOXAZOLINE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180255780-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | ACHE, CHRM1, NIT2 | GPR52 1660/4885MKNK1 2653/4885MKNK2 2026/4885 |
| US-10588317-B2 | Isoxazoline-substituted benzamides and analogues as insecticides | ACHE, CHRM1, NIT2 | GPR52 1660/4885MKNK1 2653/4885MKNK2 2026/4885 |
| US-20140350261-A1 | METHOD FOR CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE ISOXAZOLINE COMPOUND, AND OPTICALLY ACTIVE ISOXAZOLINE COMPOUND | CYP3A7, CYP2A7, CYP8B1 | GPR52 1945/4885MKNK1 3016/4885MKNK2 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.