Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | IL2 | P60568 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20261758 | 1.00 | CA1 (0.35) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL31191610 | 0.94 | RXRA (0.38) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL29397265 | 0.92 | RXRB (0.41) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL12274098 | 0.92 | RXRB (0.41) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL1694737 | 0.92 | CA1 (0.35) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL362701 | 0.92 | RXRB (0.41) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL2014009 | 0.92 | RXRB (0.41) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL29385555 | 0.92 | RXRB (0.41) | CA1CA2RXRBRXRAKDM4E | |
| Hydrochloric Acid SCHEMBL1566413 | 0.91 | RXRB (0.40) | CA1CA2RXRBRXRAKDM4E | |
| SCHEMBL16243447 | 0.91 | GPR52 (0.38) | CA1CA2RXRBRXRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214950-A1 | METHOD FOR PREPARING FLURALANER | HANGZHOU NORMAL UNIVERSITY (CN) | 2025-07-03 | — | — | US | disclosed |
| CN-118930531-A | Isoxazoline derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-117800930-A | Preparation method of fluororalrana | 杭州师范大学 | 2024-04-02 | — | — | CN | disclosed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| US-10710991-B2 | Process for the preparation of thietane derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-07-14 | — | — | US | disclosed |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-21 | — | — | US | disclosed |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-24 | — | — | US | disclosed |
| US-20190315728-A1 | PROCESS FOR THE PREPARATION OF THIETANE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-17 | — | — | US | disclosed |
| US-10266524-B2 | Process for the preparation of thietane derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-23 | — | — | US | disclosed |
| WO-2010072602-A1 | SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-07-01 | — | — | WO | disclosed |
| US-20100144797-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| US-7700808-B2 | 1-3-bis(substituted phenyl)-3-hydroxypropan-1-one or 2-propen-1-one compound, and salt thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-7662972-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| EP-2151437-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2010-02-10 | — | — | EP | disclosed |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1975149-A1 | 1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-1932836-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND HARMFUL ORGANISM-CONTROLLING AGENT | Nissan Chemical Industries, Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | CA1 1596/4885CA2 377/4885RXRB 1303/4885 |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | CHRM3, C3AR1, C9 | CA1 702/4885CA2 749/4885RXRB 689/4885 |
| US-20100144797-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT | H1-2, H1-0, H1-3 | CA1 1940/4885CA2 431/4885RXRB 1619/4885 |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | ATM, CHRM1, NAT1 | CA1 1945/4885CA2 725/4885RXRB 1458/4885 |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | C3AR1, C5, C9 | CA1 916/4885CA2 992/4885RXRB 926/4885 |
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | HCN1, CNPY2, CLIC1 | CA1 1349/4885CA2 294/4885RXRB 1420/4885 |
| US-10710991-B2 | Process for the preparation of thietane derivatives | CYP4B1, CYP1B1, CYP1A1 | CA1 1180/4885CA2 1260/4885RXRB 2835/4885 |
| US-20190315728-A1 | PROCESS FOR THE PREPARATION OF THIETANE DERIVATIVES | CYP4B1, CYP1B1, CYP1A1 | CA1 1180/4885CA2 1260/4885RXRB 2835/4885 |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | CHRM1, DDT, ATM | CA1 2192/4885CA2 878/4885RXRB 1129/4885 |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | CA1 916/4885CA2 992/4885RXRB 926/4885 |
| US-10266524-B2 | Process for the preparation of thietane derivatives | CYP4B1, CYP1B1, CYP1A1 | CA1 1180/4885CA2 1260/4885RXRB 2835/4885 |
| US-20250214950-A1 | METHOD FOR PREPARING FLURALANER | FFAR4, FFAR2, CYP2A13 | CA1 1924/4885CA2 1280/4885RXRB 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.