Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245798 | 0.87 | TSHR (0.44) | TSHRTP53MAPK1L3MBTL1NPC1 | |
| SCHEMBL16245769 | 0.87 | TSHR (0.44) | TSHRTP53LMNAMAPTAKR1C3 | |
| SCHEMBL29671369 | 0.87 | TSHR (0.44) | TSHRTP53LMNAMAPTAKR1C3 | |
| SCHEMBL29671366 | 0.83 | TP53 (0.47) | TSHRTP53ELANE | |
| SCHEMBL23248048 | 0.83 | TP53 (0.47) | TSHRTP53ELANE | |
| SCHEMBL13802284 | 0.78 | ESR2 (0.49) | TSHRTP53ELANENR3C1PGR | |
| SCHEMBL16245780 | 0.78 | LMNA (0.40) | TSHRTP53ALDH1A1LMNAPTGS1 | |
| SCHEMBL4279450 | 0.78 | TRPA1 (0.44) | TP53MAPK1L3MBTL1NPC1ALDH1A1 | |
| SCHEMBL8849716 | 0.77 | TSHR (0.60) | TSHRTP53MAPK1L3MBTL1NPC1 | |
| SCHEMBL5872655 | 0.76 | TSHR (0.63) | TSHRTP53MAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994448-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-07-31 | — | — | EP | claimed |
| US-9988592-B2 | Organic compounds | Givaudan, S.A. (CH) | 2018-06-05 | — | — | US | claimed |
| US-20170218299-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2017-08-03 | — | — | US | claimed |
| US-9656938-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2017-05-23 | — | — | US | claimed |
| US-20160075627-A1 | ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2016-03-17 | — | — | US | claimed |
| EP-2994448-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2016-03-16 | — | — | EP | claimed |
| CN-105189432-A | Improvements in or relating to organic compounds | GIVAUDAN SA | 2015-12-23 | — | — | CN | claimed |
| WO-2014180952-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-11-13 | — | — | WO | claimed |
| US-10457891-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2019-10-29 | — | — | US | disclosed |
| EP-2994448-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-07-31 | — | — | EP | disclosed |
| US-20180251706-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2018-09-06 | — | — | US | disclosed |
| US-9988592-B2 | Organic compounds | Givaudan, S.A. (CH) | 2018-06-05 | — | — | US | disclosed |
| US-20170218299-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2017-08-03 | — | — | US | disclosed |
| US-9656938-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2017-05-23 | — | — | US | disclosed |
| US-20160075627-A1 | ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2016-03-17 | — | — | US | disclosed |
| EP-2994448-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2016-03-16 | — | — | EP | disclosed |
| CN-105189432-A | Improvements in or relating to organic compounds | GIVAUDAN SA | 2015-12-23 | — | — | CN | disclosed |
| WO-2014180952-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075627-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885MAPK1 3959/4885 |
| US-20180251706-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885MAPK1 3959/4885 |
| US-20170218299-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885MAPK1 3959/4885 |
| US-10457891-B2 | Organic compounds | AOX1, TYR, ALK | TSHR 3983/4885TP53 923/4885MAPK1 3959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.