Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248 | 0.84 | MAPK1 (0.47) | CRBNMAPK1ALDH1A1TK1HPGD | |
| SCHEMBL6420314 | 0.82 | MAPK1 (0.46) | CRBNMAPK1ALDH1A1TK1HPGD | |
| SCHEMBL19031639 | 0.71 | BRD4 (0.40) | CRBNMAPK1ALDH1A1ALOX5 | |
| SCHEMBL19244642 | 0.70 | ALDH1A1 (0.35) | MAPK1ALDH1A1NPSR1TK1HPGD | |
| SCHEMBL5176789 | 0.66 | MAPK1 (0.46) | MAPK1ALDH1A1NPSR1TK1HPGD | |
| SCHEMBL27621506 | 0.66 | MAPK1 (0.46) | MAPK1ALDH1A1NPSR1TK1HPGD | |
| SCHEMBL5778743 | 0.66 | CRBN (1.00) | CRBNALDH1A1 | |
| SCHEMBL26618 | 0.66 | — | — | |
| SCHEMBL10105028 | 0.65 | KMT2A (0.40) | MAPK1ALDH1A1TK1HPGDTYMP | |
| SCHEMBL10105030 | 0.65 | CRBN (0.39) | CRBNMAPK1NPSR1TK1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714302-A4 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS INC (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0714302-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-06-05 | — | — | EP | claimed |
| WO-1994022449-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | claimed |