Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27884072 | 0.91 | AGER (0.54) | HSD11B1LTB4R2AGERMTNR1AHDAC3 | |
| SCHEMBL10207431 | 0.91 | HSD11B1 (0.56) | HSD11B1AGERMTNR1ANR1H4HDAC3 | |
| Formic Acid SCHEMBL28071336 | 0.86 | HSD11B1 (0.53) | HSD11B1AGERMTNR1ANR1H4HDAC3 | |
| SCHEMBL3117999 | 0.85 | AGER (0.48) | HSD11B1LTB4R2AGERMTNR1AGPR119 | |
| SCHEMBL13267029 | 0.85 | GPR119 (0.50) | HSD11B1LTB4R2NR1H4GPR119HDAC3 | |
| SCHEMBL14897752 | 0.85 | HSD11B1 (0.48) | HSD11B1NR1H4GPR119HDAC3HDAC1 | |
| SCHEMBL21088550 | 0.85 | HTR2A (0.44) | HSD11B1AGERMTNR1ANR1H4HDAC3 | |
| SCHEMBL3143765 | 0.84 | HSD11B1 (0.43) | HSD11B1LTB4R2AGERMTNR1AHRH4 | |
| SCHEMBL2586550 | 0.84 | HSD11B1 (0.43) | HSD11B1LTB4R2AGERMTNR1AHRH4 | |
| SCHEMBL5145400 | 0.83 | HSD11B1 (0.44) | HSD11B1AGERMTNR1AGPR119HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343019-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS, INCORPORATED | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343019-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | ARG1, ARG2, PRMT1 | HSD11B1 1790/4885LTB4R2 2260/4885AGER 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.