Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 6/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 8/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879486 | 0.82 | WDR91 (0.38) | WDR91CXCR3CCR1FAAH | |
| SCHEMBL14879817 | 0.79 | WDR91 (0.41) | WDR91CXCR3CCR1FAAH | |
| SCHEMBL14879488 | 0.72 | WDR91 (0.50) | WDR91CXCR3CCR1FAAH | |
| SCHEMBL27995135 | 0.70 | WDR91 (0.45) | WDR91CXCR3CCR1FAAH | |
| SCHEMBL16249346 | 0.68 | WDR91 (0.53) | WDR91CXCR3CCR1 | |
| SCHEMBL16249352 | 0.68 | — | — | |
| SCHEMBL14879485 | 0.67 | WDR91 (0.42) | WDR91CXCR3CCR1FAAH | |
| SCHEMBL10207452 | 0.65 | DRD2 (0.38) | — | |
| SCHEMBL28545624 | 0.61 | NPC1 (0.50) | WDR91CXCR3CCR1 | |
| SCHEMBL28793250 | 0.60 | CXCR3 (0.51) | CXCR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343019-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS, INCORPORATED | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343019-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | ARG1, ARG2, PRMT1 | WDR91 975/4885CXCR3 1039/4885CCR1 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.